[Comparative study of some breast cancer risk factors in patients with breast cancer and leukemia in Ahvaz Shafa hospital]

Breast cancer includes 32% of women's cancer is the most common malignancies in women and is the reason for 19% of cancer-dependent mortality. The aim of this study was comparison between some breast cancer risk factors in patients with breast cancer and leukemia in Ahvaz Shafa Hospital. In this retrospective and analytic study,167 patients with breast cancer were compared with 317 patients with leukemia in a two- year period. The risk factors included age, OCP usage, smoking, positive familial history of breast cancer and positive history of benign breast disease. Odds ratio index was used for statistical data analysis. Breast cancer was seen more in 41 to 50 years old women. Familial history of breast cancer and history of benign breast disease were effective risk factors and smoking and, OCP usage increased the risk of developing breast cancer in our study. The results showed that some of the breast cancer risk factors are preventable, such as changes in lifestyle, regular examinations, especially about persons with a familial history of breast cancer or benign breast diseases which in turn can influence early diagnosis. Screening tests such as mammography are also useful in early diagnosis and improved prognosis of breast cancer

[Comparison of lipids and lipoprotein levels of cord blood in neonates in Ahwaz city with the same parameters in nelson textbook of pediatrics]

Adult cardiovascular disease has its roots in childhood, Various surveys have shown a significant correlation between early atherosclerotic changes identified at autopsy of children and young adults, and both total cholesterol [TC] and low-density lipoprotein [LDL cholesterol] levels. The hypercholesterolemic neonates time for diagnosis of high risk neonate infants. The aim of this study is to compare the lipids and lipoproteins levels of cord blood with the same parameters in Nelson textbook of pediatrics. This is a cross sectional study on umbilical cord blood of 243 full term newborn infants [114 females and 129 males] who were born at the Razi Hospital of Ahwaz University from March to September of 2002. For the collection of data, we used the nonprobabilitic sampling. Complicated and abnormal cases were eliminated. The mean of TC, LDL-C, HDL-C and TG were 81.02+/-19.75mg/dl, 48.92+/-6.39 mg/dl, 25.09+/-7.34 mg/dl and 42+/-29. 10 mg/dl. The result showed that the mean of T.C., LDL C and TG was significantly more than that of Nelson textbook [P=0.0001]. The mean of HDL C. was significantly less than that of Nelson textbook [P=0.0001]. Also the prevalence of hypercholesterolemia in neonatal infants is significantly more than that of Nelson textbook. In this study, the mean of lipids and lipoproteins was compared between males and females. The mean of TC and LDL C. in females is significantly more than male neonates [P=0.016 and P0.007]. Therefore, this community is at high risk. Because the neonates with hypercholesterolemia will be more liable to face this problem in adulthood, measuring of cord blood lipids and lipoproteins is a priority in this community. Lipids profiles of parents and other 1st degree relatives are also necessary to establish whether there is a dominantly inherited defect responsible for the hypercholesterolemia